Stress and Mood Support Supplements

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Quite a few circumstances can cause acute and chronic stress. You cannot always avoid things that cause anxiety (e.g., work, school, interpersonal relationships, emergencies, etc.). However, there are ways to cut down on the effects they will have on your overall well being. Some supplements will allow you to strengthen your body against the effects of stress.

Understanding how stress affects your body can help you learn about the best ways to keep yourself happy and healthy. We will give you a full overview of all our supplements, the ingredients that make them up, and additional ways to combat symptoms like anxiety, depression, and a weakened immune system, which are all effects of stress. 

The Effects of Stress on Your Body

Stress is a natural reaction that helps kick start the "flight or fight" mechanism when necessary. We all have hormones designed to flood our systems during times of danger to keep us alert and safe. However, this critical system response can become a negative thing when it is triggered continuously by everyday situations. This can be caused by mineral and vitamin deficiencies that lower the body's defenses against the effects of stress.

Neurotransmitters such as dopamine, adrenaline, and norepinephrine are released during times of heightened nervousness, and they can play havoc on both the brain and the Endocrine system. In addition, vitamin deficiencies will cause an imbalance of neurotransmitters serotonin, dopamine, histamine, and GABA. Adding a supplement to your diet to replace those deficiencies and shore up your body's systems can help alleviate those symptoms.  

Chronic stress can have serious adverse health effects. Studies have reported numerous lasting impacts from mental and physical stress in approximately 73%-77% of adults in the United States (source). This has the potential to impact work, school, personal relationships, and social interactions. The effects of stress can be broken down into two main categories, physical and psychological.

Psychological Symptoms

The brain and nervous system rely on specific chemicals and hormones to stay healthy. When those are thrown out of balance, it can cause problems, and the primary way they manifest is through a change of behavior. Anyone who has been anxious knows the agitated, irritability that always comes with it. Reactions to continued stress can cause psychological symptoms such as those listed below.

  • Anxiety
  • Depression
  • Inability to focus
  • Extreme mood changes
  • Unusual irritability
  • Memory issues

Physical Symptoms

If you have ever dealt with a period of anxiety, then you probably know how it can slow down your body and leave you feeling completely drained. These are natural responses to acute and chronic stress. Some of the physical symptoms include the following.

  • Increased blood pressure
  • Changes in sleeping patterns (e.g., insomnia, oversleeping)
  • Changes in eating pattern (e.g., loss of appetite, overeating)
  • Flu-like symptoms (e.g., headache, nausea, diarrhea, constipation, body aches, etc.)
  • Lethargy and unusual loss of energy
  • Increased risk factor for obesity and heart disease

Supplements For Stress

Our supplements provide concentrated nutrients that you can add to your diet for a quick boost. There are many available, and they vary from synthetic to natural extracts-the following supplement ingredients are explicitly used to target stress and stress-related symptoms like anxiety, sleep issues, and depression. Our products often provide more than one health benefit.

Elemental SAMe 400mg (30 Enteric-Coated Tablets)
Elemental SAMe 400mg (30 Enteric-Coated Tablets)
Elemental SAMe 400mg (30 Enteric-Coated Tablets)
Elemental SAMe 400mg (30 Enteric-Coated Tablets)

S-Adenosylmethionine (SAMe)

SAMe is a compound that naturally occurs in the human body where it assists with regulating hormones and maintaining the health of cell membranes. Sometimes it is necessary to get additional SAMe if your body is unable to produce enough. A synthetic version is used in supplements, and studies have shown that it can alleviate stress, depression, liver disease, and osteoarthritis

Learn more about SAMe
5-HTP (Griffonia Seed Extract) 100mg (60 Capsules)
5-HTP (Griffonia Seed Extract) 100mg (60 Capsules)
5-HTP (Griffonia Seed Extract) 100mg (60 Capsules)
5-HTP (Griffonia Seed Extract) 100mg (60 Capsules)
5-HTP (Griffonia Seed Extract) 100mg (60 Capsules)
5-HTP (Griffonia Seed Extract) 100mg (60 Capsules)
5-HTP (Griffonia Seed Extract) 100mg (60 Capsules)
5-HTP (Griffonia Seed Extract) 100mg (60 Capsules)
5-HTP  (Griffonia Seed Extract) 100mg (60 capsules)

5-HTP (5-Hydroxytryptophan)

5-HTP is an amino acid that is created from tryptophan. For our products, it is manufactured from Griffonia Simplicifolia seeds. When used in moderate doses, this compound can help with anxiety, mood disorders, sleep, and panic through increasing serotonin and other neurotransmitters.

Learn more about 5-HTP
NOW St. John's Wort 300 mg - 100 Veg Capsules
NOW St. John's Wort 300 mg - 100 Veg Capsules
Suggested Usage Now St. Johns Wart 300mg Veg Capsule.
Supplemental Panel Now St. Johns Wart 300mg Veg Capsule.

St. John's Wort Extract

Herbalists have been using various parts of the St. John's Wort plant for hundreds of years to treat all sorts of mood disorders. It is all-natural and can be combined with other things like 5-HTP to increase the positive effects. As an over-the-counter medicine and supplement, it is used to treat anxiety, depression, and sleeping disorders.

Learn more about St. Johns Wort
Kava Kava Root Extract, 30% Full-Spectrum 200mg (60 Capsules)
Kava Kava Root Extract, 30% Full-Spectrum 200mg (60 Capsules)
Kava Kava Root Extract, 30% Full-Spectrum 200mg (60 Capsules)
Kava Kava Root Extract, 30% Full-Spectrum 200mg (60 Capsules)
Kava Kava Root Extract, 30% Full-Spectrum 200mg (60 Capsules)
Kava Kava Root Extract, 30% Full-Spectrum 200mg (60 Capsules)
Kava Kava Root Extract, 30% Full-Spectrum 200mg (60 Capsules)
Kava Kava Root Extract, 30% Full-Spectrum 200mg (60 Capsules)
Kava Kava Root Extract, 30% Full-Spectrum 200mg (60 Capsules) Supplement Facts Label

Kava Kava

This is another ancient medicine that has been passed down for generations. It contains kavapyrones, which produce feelings of happiness, calm, and relaxation. Scientific studies have shown that Kava Kava root extract can reduce stress and anxiety, relax muscles, and help manage seizures.

Learn more about Kava Kava

Omega-3's Fatty Acids

These fatty acids can be harvested from flaxseed or fish and are most often found in fish oil supplements. Omega-3's are prevalent in the membranes of the brain. When taken as a supplement, they are known to help with anxiety, lower blood pressure, and slow plaque development in arteries

Learn more about Omega-3's
Melatonin 3mg (180 Lozenges)
Melatonin 3mg (180 Lozenges)
Melatonin 3mg (180 Lozenges)


The hormone melatonin is used to regulate sleep patterns. It is available over the counter to help with insomnia. Having a good night's sleep can be vital for fighting stress, which means that taking it will help when you cannot fall asleep due to anxiety or a mood disorder stemming from stress.

Learn more about Melatonin
Vitamin B-50 Complex 510mg (90 Capsules)
Vitamin B-50 Complex 510mg (90 Capsules)
Vitamin B-50 Complex 510mg (90 Capsules)
Vitamin B-50 Complex 510mg (90 Capsules)
Vitamin B-50 Complex 510mg (90 Capsules)
Vitamin B-50 Complex 510mg (90 Capsules)
Vitamin B-50 Complex 510mg (90 Capsules)
Vitamin B-50 Complex 510mg (90 Capsules)

B Complex Vitamins

B vitamins are all unique and play essential parts in keeping your body healthy. They include vitamins B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), B6 (pyridoxine), and B12 (folic acid, cobalamins, biotin). Some vitamin B compounds can include zinc or vitamins C and E as well. They provide various benefits such as increased brain function, higher energy levels, a decrease in stress and anxiety, healthy cell growth, and they can help prevent infections.

Learn more about B-Complex
Magnesium Citrate 400mg (90 Capsules)
Magnesium Citrate 400mg (90 Capsules)


Magnesium is a mineral that promotes healthy bone growth, heart rhythm, and blood pressure. This is something that must be included as a part of a healthy diet. There are a few types available in supplement form. Magnesium glycinate is the best for lowering anxiety, fighting chronic stress symptoms, and encouraging sleep. A magnesium deficit can lead to an increase in various forms of inflammation, heart disease, and creates a higher risk factor for diabetes.

Learn more about Magnesium

Other Noteworthy Supplements for Stress Reduction

Rhodiola Rosea

It is known by multiple names, including "arctic root" or "golden root", and this plant grows in various cold regions all around the world. Herbalists have used it for years to strengthen the body and mind. This plant is an adaptogen, meaning it can help you resist the negative symptoms of stress and anxiety.


Glycine is an amino acid that is naturally produced. This neurotransmitter affects mood, appetite, and various aspects of cognition. Taking glycine supplements can help lower the body's temperature and encourage sleep. It also has some calming properties.


The plant Withania Somnifera has a few different names you might know it by including "gooseberry", "ashwagandha", or "winter cherry." It is a herb that can help the body fight stress. It has also been shown to help with lowering blood sugar, depression, easing inflammation and anxiety, and lowering cortisol levels.


Theanine is an amino acid that comes from mushrooms as well as both black and green tea leaves. It relieves stress by encouraging sleep and calmness. Some of the other health benefits of taking L-theanine include stress reduction, better focus, heightened immunity, and it helps keep blood pressure in normal limits among individuals prone to hypertension

Valerian Root

Valerian is a perennial flower. The roots have been used medicinally for generations. In supplement form, it can cause feelings of calm, reduce stomach cramps, improve sleep, and provide relief from both anxiety and stress. Unlike some other ingredients, valerian root has so few possible side effects that it is safe to consume on a daily basis as needed making it ideal for anyone with chronic sleep or mood disorders.


This herb is also known as the "water hyssop", "Indian pennywort", and "brahmin." It protects the brain from cognitive decline and has been shown to help with Alzheimer's, forgetfulness, anxiety, insomnia, joint pain, depression, and ADHD, among other benefits. You can use this to keep your mind healthy and sharp.


This phospholipid carries messages between brain cells, and it can be found in the cell membranes. It has many functions, including anxiety relief and protecting against age-related cognitive decline. Supplements with this ingredient are used for ADHD, athletics, stress reduction, and depression. The phosphatidylserine that you will find in our products is made from soy or cabbage.

Gamma-Aminobutyric Acid (GABA)

This amino acid is the primary inhibitory neurotransmitter produced in the brain. It is synthesized from glutamate. GABA is excellent for growing muscles, burning fat, and relieving anxiety. This makes a perfect addition to a diet aimed towards losing weight in addition to being a mood stabilizer.

Other Measures for Stress Reduction

Supplements are not the only lifestyle changes that you can make to decrease your stress levels. There are plenty of lifestyle changes and therapeutic options available. Below are some of the most common holistic approaches to destressing.


Practicing mindfulness through meditation and other relaxation techniques (e.g., yoga, massage therapy, breathing exercises, hypnotherapy, etc.) can be beneficial. It can be used together with supplements for better results.

Nutritional Meals and Exercise

A balanced and healthy body is going to be able to recover from stressful moments faster and easier. Nutritional meals with the added vitamins will be helpful, as will regular exercise. A healthy body supports a healthy mind.

Positive Thinking

Studies show that having a positive outlook on life can significantly lower everyday stress. (Source) one way it works is by allowing you to think of more positive coping strategies. There are many ways to find positivity in each day. You can help others, look for beauty in the world around you, or focus on your spirituality if that is something that brings you calm and joy.

Get Plenty of Sleep

Many people are unaware of how connected a good night's sleep is to mood and mental health. It is not only the amount of sleep you are getting but the quality that matters. Stress can be reduced if you create a set sleep schedule that gives you between seven and nine hours of sleep. These restful periods will allow your body to fight stress and related symptoms.


With so many vitamins and minerals included in supplements, it is important to know their possible advantages and effects. Below are some popular questions about some of our more common ingredients.

What vitamin deficiency can cause anxiety?

Several studies have pinpointed a number of vitamins that are vital for avoiding anxiety. Deficiencies in these can lead to increased stress responses, including sleep disruption, anxiety, and mood swings. They include the following vitamins and minerals. (Source)

  • B6 and other B-vitamins
  • Vitamins C, D, and E
  • Zinc
  • Magnesium
  • Calcium
  • Iron

What is the best supplement to lower cortisol?

There are several areas of the body that might lead to an overproduction of cortisol in the body. An overactive pituitary gland is a common one. Once cortisol levels are raised, it can lead to body aches and fatigue, swollen legs, mood swings, anxiety, and weight gain. There are several supplements with ingredients that can lower cortisol levels. The best example is ashwagandha. This herb has been known to reduce cortisol when used consistently. (Source)

Does B12 help with anxiety?

B12 keeps the body's blood cells and nerves healthy. A deficiency can cause depression, anxiety, and even hallucinations. Once you begin taking B12 to alleviate these symptoms, it can take 48 to 72 hours before changes are noticeable. B12 supplements are also known to help with depression and osteoarthritis.

Does turmeric lower cortisol?

Turmeric is a spice that has a lot of useful properties. It can decrease anxiety, inflammation, and cortisol while increasing serotonin. It also works as an antioxidant.

Article Sources

  • Kava Kava for anxiety
  • Omega-3 fatty acids and stress
  • Magnesium and stress
  • Influence of S-adenosyl on chronic stress

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