Our new LeptiFit™ Leptin Control Formula is a complex blend of polysaccharides, polyphenols, fatty acids, and amino acids that work synergistically to increase weight loss by increasing satiety (the feeling of being full), decreasing leptin resistance, reducing C-Reactive Protein levels, and decreasing inflammation. Two of the core steps to loosing weight are controlling hunger and inflammation.

The science behind this product is rather complex. Leptin is a hormone produced by adipocytes (fat cells) that regulates body fat storage by modulating satiety, glycemic control and metabolism. When everything is working properly, leptin helps to keep adipose tissue (fat) within a normal, healthy range. However, diet and stress can lead to chronic inflammation and leptin resistance--chronic inflammation increases levels of C-Reactive Protein which binds to leptin, preventing it from doing its job. When leptin resistance occurs, the body does not get the signal to stop eating, leaving one feeling hungry even after having consumed enough calories. LeptiFit™ is designed to help reduce leptin resistance, allowing leptin to properly control hunger. As an added bonus, LeptiFit™ naturally reduces C-Reactive Protein, which is an indicator of heart disease risk. That's a double-benefit to cardiovascular health: weight loss, and reduced C-Reactive Protein levels.

Our new LeptiFit™ Leptin Control Formula is a complex blend of polysaccharides, polyphenols, fatty acids, and amino acids that work synergistically to increase weight loss by increasing satiety (the feeling of being full), decreasing leptin resistance, reducing C-Reactive Protein levels, and decreasing inflammation. Two of the core steps to loosing weight are controlling hunger and inflammation.

The science behind this product is rather complex. Leptin is a hormone produced by adipocytes (fat cells) that regulates body fat storage by modulating satiety, glycemic control and metabolism. When everything is working properly, leptin helps to keep adipose tissue (fat) within a normal, healthy range. However, diet and stress can lead to chronic inflammation and leptin resistance--chronic inflammation increases levels of C-Reactive Protein which binds to leptin, preventing it from doing its job. When leptin resistance occurs, the body does not get the signal to stop eating, leaving one feeling hungry even after having consumed enough calories. LeptiFit™ is designed to help reduce leptin resistance, allowing leptin to properly control hunger. As an added bonus, LeptiFit™ naturally reduces C-Reactive Protein, which is an indicator of heart disease risk. That's a double-benefit to cardiovascular health: weight loss, and reduced C-Reactive Protein levels.

Leptin is a hormone produced by adipocytes (fat cells) that regulates body fat storage by modulating satiety, glycemic control and metabolism. Leptin regulates appetite by binding to sites in a region of brain called the hypothalamus. Leptin triggers the sensation of satiety, giving the feeling of having eaten enough.(Sahu, 2003) Generally speaking when a person is properly nurished, serum leptin levels increase, and hunger levels decrease. Additionally leptin plays a role in metabolic regulation and helps the body utilize stored fat.(Wang, 2005)

If everything is working properly, when the body has accumulated enough stored fat, adipocytes release leptin. The leptin crosses the blood brain, signaling you to stop eating sooner which stops the accumulation of fat.

Leptin Resistance is a chronic inflammatory problem that can lead to slow, steady weight gain. When researchers began investigating the role of leptin in the body, the quickly ran into a paradox. While leptin is known to control hunger, researchers found that overweight people frequently have extremely elevated plasma leptin levels. As counterintuitive as this seems, researcher were able to determine that leptin resistance was responsible for this problem.

Much in the same way type-2 diabetics become insulin resistant, people can become leptin resistant. Unlike diabetics, treatment isn't as simple as injecting more leptin into the body. The problem is two-fold. First obesity and weight gain are associated with higher inflammation. The higher inflammation is associated with higher levels of C-Reactive Protein (CRP). A 2006 study conducted by researchers at the University of Pittsburgh shows that elevated levels of CRP inhibit leptins role in controlling appetite.(Chen, 2006) CRP aggressively binds to leptin, creating a large molecule that can not cross the blood-brain barrier to the hypothalamus,therefore the leptin never gets to the hypothalamus and the body never gets the message to stop eating. This in turn leads to more weight gain. Which causes more and more leptin and CRP to be produced, soon inflammation levels elevate, cholesterol and triglyceride levels increase leading to a feedback loop that leads to more and more weight gain, higher and hirer CRP, cholesterol levels, and triglycerides and of course greater leptin resistance.

LeptiCore® is a patented, proprietary blend of plant polysaccharides, esterified fatty acids, pomegranate polyphenols, beta carotene, Klamath blue green algae and phenylethylamine that work synergistically to reduce leptin resistance and CPR and increase satiety.

LeptiCore® also enhances cell membrane stability for improved cellular communication between the liver and adipose tissues for enhanced fatty acid utilization leading to regional fat loss. In addition, modulation of membrane-based inflammatory markers helps to reduce the inflammatory component of fat gain. It is here that LeptiCore® differs from other leptin regulating supplements; the ingredients in LeptiCore®’s proprietary blend, have been shown to reduce CRP.

Other benefits of Lepticore’s weight loss formula is the ability to curve your appetite and address emotional eating. Serotonin, a vital neurotransmitter, is involved in a wide range of behavioral functions in the body, including mood, sleep and appetite control. Studies show that serotonin affects eating behavior and body weight. Increased plasma levels of serotonin are associated with decreased food intake, reduced weight gain and increased energy expenditure. Phenylethylamine (PEA) is an endogenous neuromodulating compound known to increase natural serotonin concentration and elevate mood. PEA is the compound found in dark chocolate that provides the feeling of well being.

In a yet to be published randomized, double-blind, placebo-controlled 8 week clinical study involving 90 obese men and women, LeptiCore® showed some impressive results. Over the course of the study participants in the LeptiCore® group say a 6.95% reduction in body weight (an average of 14.5 pounds), a 4% decrease in body fat levels, and a 2 inch reduction in average waist and hip circumference. But that's not all, plasma total cholesterol levels were reduced by an average of 27.48%. Plasma LDL ("bad") cholesterol levels were reduced by an average of 19.77% while plasma HDL ("good") cholesterol was increase by an average of 19.12%. Plasma triglyceride level were decrease by 16.45% Perhaps most importantly, C-Reactive Protein levels were reduced by nearly 30%, while serotonin levels were increased by nearly 39%. The differences are nothing short of astounding. LeptiFit™ combines LeptiCore® with the other ingredients to for even greater results and cardiac support.

Over the past decade, green tea and green tea extract have been the subject of a significant amount of research. Studies have linked green tea polyphenols to a myriad of potential benefits, including reduced risk of "all-cause mortality." (Kuriyama, 2006) However, our reason for including it in this formula are two fold; studies have found that green tea may aid in weight loss and it may provide cardiac benefits.(Alexopoulos, 2008)

L-Theanine is an amino acid that like phosphatidyl serine works in the brain. It readily crosses the blood brain barrier and increases the production of Gamma-aminobutyric acid (GABA), and increases levels of dopamine and serotonin, creating a feeling of relaxation and well being without drowsiness. There is also evidence that it may increase alpha-wave production in the brain, the brain wave cycle that occurs during periods of relaxation, sleep initiation, and waking. Therefore l-Theanine may improve sleep.

L-Carnitine

L-Carnitine is an amino acid-like substance. It bears many resemblances to amino acids and is usually grouped under this heading, however L-Carnitine is not used as a neurotransmitter or in protein synthesis and therefore does not meet the definition of an amino acid. L-Carnitine increases muscle strength and energy, and helps the body to burn fat more efficiently. It is used by the body to transport long chain fatty acids to the mitochondria in your cells, where the fatty acids are used to create energy. Since this fat burning is such a major source of muscular energy, deficiencies in L-Carnitine are manifested as low energy levels and muscular weakness. L-Carnitine deficiencies can also appear as mental confusion or cloudiness, heart pain and weight gain. L-Carnitine seems to help support a health heart, and it is well known to help in the treatment of heart pain (usually induced by physical stress). L-Carnitine may also be helpful to the liver and heart in several ways, most notably by helping to prevent fatty build-ups in the heart and liver.