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Resveratrol Supplements & Products
What is Resveratrol?
Resveratrol is a phenolic compound that naturally occurs in some plants and has been found to have strong antioxidant activity when ingested. Plants create resveratrol to protect themselves against the effects of poor growing conditions, severe weather and attacks by insects and disease. In animals, resveratrol has been shown to reduce the oxidation of LDL cholesterol, total cholesterol and the risk of cardiovascular disease.
Resveratrol in the News
Resveratrol has been in the news quite frequently over the past two and a half years sparked by new studies on animals that have shown that resveratrol supplementation has the same beneficial effects on longevity as a restricted-calorie diet -- specifically, up to a 40% increase in life span!
In addition, the popular press has run a number of stories about Resveratrol, including CBS News' 60 Minutes (January 25, 2009) [see the embedded video below], a segment in Barbara Walter's ABC News special Live to 150... Can You Do It? (April 1, 2008), the Wall Street Journal 10/30/06, New York Times, CNN.com, Washington Post, San Francisco Chronicle, and Boston Globe on 11/02/06.
Resveratrol and Health
Numerous studies showing the benefits of moderate red wine consumption on health sparked the research on resveratrol over a decade ago. Red wine differs from white in that it is fermented with the resveratrol-containing grape skins present. This fermentation process imparts the resveratrol (and other anitoxidants in the grape skin) into the finished wine. Early studies suggested that the intake of red wine (and therefore resveratrol) may yield health benefits. Over the past decade, researchers have focused on resveratrol, specifically.
What You Need to Know When Shopping for Resveratrol:
We offer several products containing resveratrol. Click on the image of any product, below, for more detailed information on each.
You should know that in nature, resveratrol exists in two different isomers, trans-resveratrol and cis-resveratrol. These prefixes, "trans" and "cis", refer to the shape of the molecule. Researchers have identified trans-resveratrol as the biologically active of the two isomers. Therefore, as a consumer, you don't care about "resveratrol", you care about "trans-resveratrol".
Our Extra Strength Resveratrol has the highest content of trans-resveratrol per capsule, 325mg, than any other product we know of. This offers a tremendous value to those looking for high amounts of Resveratrol. When comparing products, be sure to look at a product's Supplement Facts Panel (ours is below) and look for a line item listing the amount of "trans-resveratrol" per capsule. Review our Certificate of Analysis and compare our Extra Strength Resveratrol to others.
Consumer Alert: We have been told by many customers that several companies have been taking advantage of the recent interest in resveratrol to lure customers with "free trial offers" that are followed a week later by "mandatory" shipments costing the customer $80 or more. It is our belief that companies who practice these tactics give our industry a bad name.
Please be assured that our prices, below, are valid for your first order, your second order, your third order, and so on -- there are no hidden fees or fine print; there is never any obligation to ever buy from us again. If you enroll in our optional Convenience Plan, you will be in complete control over your shipments; there is no mandatory enrollment period, whatsoever. We have been in business for more than 12 years, we existed before resveratrol was popular, and we will exist long after people forget about the story on 60 Minutes. We believe in honesty and integrity, and we guarantee every product we sell with an unconditional 60-Day Money Back Guarantee.
If you follow the news, then you have likely heard of resveratrol, an antioxidant commonly found in red wine, grape skins and other plants.
Many people heard about resveratrol for the first time on Sunday, January 25, 2009, when the CBS News program 60 Minutes aired a segment on the promising new research surrounding resveratrol. You can watch this segment to the right.
CBS News Correspondent Morley Safer interviews Harvard University researchers Christoff Westphal and David Sinclair, who have been pursuing the genetic link between resveratrol and enzymes called sirtuins for the past 5 years.
Sirtuins are a recently discovered class of enzymes that appear to control the aging process. In this video, Safer, Westphal and Sinclair discuss the incredible results from ongoing research aimed at identifying and isolating the exact component of resveratrol responsible for these lab results, in an effort to manufacture a pharmaceutical from this naturally-occurring compound.
Previously "Live to 150...Can You Do It?" an ABC News and Barbara Walters Special (April 1, 2008), Barbara Walters talked to researchers about the stunning research on longevity and Resveratrol. A little over a year earlier, researchers examining resveratrol made front-page news with their studies showing that resveratrol increased the life expectancy of lab animals by over 40%! Based on the results of this early research, we are expecting much more research to be done in the near future; we'll keep you posted.
Resveratrol is believed to be the plants' natural defense against adverse growing conditions and fungal attacks. While resveratrol is commonly found in red wine, it is only available in small amounts and those amounts vary greatly from wine to wine and bottle to bottle.1
Subscribers to our free monthly newsletter know all about this ongoing research. Below is a brief summary of the biggest headline-grabbing research results:
Resveratrol & Longevity
Resveratrol has been in the news over the last few years due to the results of several animal studies that found a link between resveratrol intake and significantly extended life spans. So far those studies have not been conducted on long-lived animals like humans. But the results of the animal studies are impressive to say the least. In 2003 researchers found that resveratrol increased the life span of a yeast by 70%.2 A follow-up 2006 study found a 56% increase in life span among a particular worm, Caenorhabditis elegans, and the common fruit fly, Drosophila melanogaster.3 In 2006, a study of a short-lived fish also found an extension of the animals' lives and revealed that the resveratrol delayed the onset of age-related markers.4,5 But the real break-through news on resveratrol came in the form of two studies published in the fall of 2006.6 The first of the two studies was published in the highly regarded scientific journal Nature, and found that resveratrol not only extended life by 40% in lab mice, but those same mice were eating a high calorie, high-fat diet without developing the ill-effects, such as diabetes and heart disease, that are normally associated with that kind of diet. The mice still got fat, but they stayed healthy.
Supplement Facts Serving Size: 2 Capsules Servings per container: 30
Amount Per Serving
% Daily Value
Vitamin C (ascorbyl palmitate)
120 mg
200%
Vitamin B-1 (thiamine)
1.5 mg
100%
Vitamin B-2 (riboflavin)
1.7 mg
100%
Inositol hexaniacinate
20 mg
100%
Vitamin B-6 (pyridoxine)
2 mg
100%
Folic Acid (folate)
400 mcg
100%
Vitamin B-12 (cobalamin) 1%
6 mcg
100%
Vitamin B-5 (pantothenic acid)
10 mg
100%
Selenium (from selenium AAC 1% )
200 mcg
286%
Milk Thistle Extract (80% silymarin)
300 mg
†
Citrus Bioflavonoids
240 mg
†
Alpha Lipoic Acid
100 mg
†
D, L Methionine
100 mg
†
Glycine
100 mg
†
Artichoke Flower/sasparilla root (ext. 5:1)
25 mg
†
Resveratrol (Protykin 50%)
15 mg
†
Indole-3-carbinol
10 mg
†
†Daily value not established.
Other ingredients: Magensium Stearate, silicon dioxide, cellulose (plant fiber).
The following product is not labeled for resveratrol content. However, it is very popular with our customers who purchase resveratrol because many of them want to ensure they are getting all the beneficial compounds found in grapes and red wine. This is a complete grape skin and grape seed product.
Supplement Facts Serving Size: 2 Capsules Servings per container: 90
Amount Per Serving
% Daily Value
Grape Seed Extract (95% OPCs)
200 mg
†
Grape Skin Extract 30%
100 mg
†
Red Wine Extract 30%
60 mg
†
†Daily value not established.
Other ingredients: Cellulose (plant fiber), magnesium stearate (vegetable source).
References
Jellin JM, Gregory PJ, Batz F, Hitchens K, et al. Pharmacist's Letter/Prescriber's letter Natural Medicines Comprehensive Database. 8th ed. Stockton, CA: Therapeutic Research Faculty; 2006:pg 1247-1248
Howitz, K. T., K. J. Bitterman, et al. (2003). "Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan." Nature 425(6954): 191-6.
Wood, J. G., B. Rogina, et al. (2004). "Sirtuin activators mimic caloric restriction and delay ageing in metazoans." Nature 430(7000): 686-9.
Valenzano, D. R., E. Terzibasi, et al. (2006). "Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate." Curr Biol 16(3): 296-300.
Valenzano, D. R., E. Terzibasi, et al. (2006). "Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate." Curr Biol 16(3): 296-300.
Baur, J. A., K. J. Pearson, et al. (2006). "Resveratrol improves health and survival of mice on a high-calorie diet." Nature 444(7117): 337-42.
Lagouge, M., C. Argmann, et al. (2006). "Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha." Cell 127(6): 1109-22.
This website and these statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Please consult a properly trained medical practitioner for medical advice.